A common breeding practice for pet dogs is mating between close relatives (e.g. between half- and full siblings).[81] Inbreeding depression is considered to be due largely to the expression of homozygous deleterious recessive mutations.[82] Outcrossing between unrelated individuals, including dogs of different breeds, results in the beneficial masking of deleterious recessive mutations in progeny.[83]

In domestic dogs, sexual maturity happens around six to twelve months of age for both males and females,[17][68] although this can be delayed until up to two years old for some large breeds. This is the time at which female dogs will have their first estrous cycle. They will experience subsequent estrous cycles semiannually, during which the body prepares for pregnancy. At the peak of the cycle, females will come into estrus, being mentally and physically receptive to copulation.[17] Because the ova survive and are capable of being fertilized for a week after ovulation, it is possible for more than one male to sire the same litter.[17]
The genetic divergence between dogs and wolves occurred between 40,000–20,000 years ago, just before or during the Last Glacial Maximum.[27][2] This timespan represents the upper time-limit for the commencement of domestication because it is the time of divergence and not the time of domestication, which occurred later.[27][28] The domestication of animals commenced over 15,000 years ago, beginning with the grey wolf (Canis lupus) by nomadic hunter-gatherers.[27] The archaeological record and genetic analysis show the remains of the Bonn–Oberkassel dog buried beside humans 14,200 years ago to be the first undisputed dog, with disputed remains occurring 36,000 years ago.[2] It was not until 11,000 years ago that people living in the Near East entered into relationships with wild populations of aurochs, boar, sheep, and goats.[27]
Please note that regardless of pet type, we always put safety first. Sometimes pets can stress in new situations. If we feel your pet is too stressed or showing any potential health concern, we may opt to conclude the grooming appointment in order to do what's best for them. Your stylist can help recommend a grooming service for a smooth introduction, such as a Mini Make-Rover. For any potential health concern your stylist will refer you to your veterinarian.