^ Jump up to: a b Freedman, Adam H.; Gronau, Ilan; Schweizer, Rena M.; Ortega-Del Vecchyo, Diego; Han, Eunjung; Silva, Pedro M.; Galaverni, Marco; Fan, Zhenxin; Marx, Peter; Lorente-Galdos, Belen; Beale, Holly; Ramirez, Oscar; Hormozdiari, Farhad; Alkan, Can; Vilà, Carles; Squire, Kevin; Geffen, Eli; Kusak, Josip; Boyko, Adam R.; Parker, Heidi G.; Lee, Clarence; Tadigotla, Vasisht; Siepel, Adam; Bustamante, Carlos D.; Harkins, Timothy T.; Nelson, Stanley F.; Ostrander, Elaine A.; Marques-Bonet, Tomas; Wayne, Robert K.; Novembre, John (16 January 2014). "Genome Sequencing Highlights Genes Under Selection and the Dynamic Early History of Dogs". PLOS Genetics. 10 (1): e1004016. doi:10.1371/journal.pgen.1004016. PMC 3894170. PMID 24453982.
According to the Humane Society of the United States, 3–4 million dogs and cats are euthanized each year in the United States and many more are confined to cages in shelters because there are many more animals than there are homes. Spaying or castrating dogs helps keep overpopulation down.[75] Local humane societies, SPCAs, and other animal protection organizations urge people to neuter their pets and to adopt animals from shelters instead of purchasing them.
Neutering reduces problems caused by hypersexuality, especially in male dogs.[76] Spayed female dogs are less likely to develop some forms of cancer, affecting mammary glands, ovaries, and other reproductive organs.[77] However, neutering increases the risk of urinary incontinence in female dogs,[78] and prostate cancer in males,[79] as well as osteosarcoma, hemangiosarcoma, cruciate ligament rupture, obesity, and diabetes mellitus in either sex.[80]
You may need to pluck ear hairs from time to time. Ask a veterinarian or professional groomer to show you how to pluck the hairs from your dog's ear safely and correctly. Ear powder makes the process easier and quicker by giving added gripping power to the slippery ear hairs. Be very careful when using hemostats as they may poke inside their ear if used incorrectly or when the dog jerks their head.

In 1758, the Swedish botanist and zoologist Carl Linnaeus published in his Systema Naturae the binomial nomenclature – or the two-word naming – of species. Canis is the Latin word meaning "dog",[21] and under this genus he listed the dog-like carnivores including domestic dogs, wolves, and jackals. He classified the domestic dog as Canis familiaris, and on the next page he classified the wolf as Canis lupus.[3] Linnaeus considered the dog to be a separate species from the wolf because of its cauda recurvata - its upturning tail which is not found in any other canid.[22]

The genetic divergence between dogs and wolves occurred between 40,000–20,000 years ago, just before or during the Last Glacial Maximum.[27][2] This timespan represents the upper time-limit for the commencement of domestication because it is the time of divergence and not the time of domestication, which occurred later.[27][28] The domestication of animals commenced over 15,000 years ago, beginning with the grey wolf (Canis lupus) by nomadic hunter-gatherers.[27] The archaeological record and genetic analysis show the remains of the Bonn–Oberkassel dog buried beside humans 14,200 years ago to be the first undisputed dog, with disputed remains occurring 36,000 years ago.[2] It was not until 11,000 years ago that people living in the Near East entered into relationships with wild populations of aurochs, boar, sheep, and goats.[27]
In a study of seven breeds of dogs (Bernese mountain dog, basset hound, Cairn terrier, Epagneul Breton, German Shepherd dog, Leonberger, and West Highland white terrier) it was found that inbreeding decreases litter size and survival.[84] Another analysis of data on 42,855 dachshund litters found that as the inbreeding coefficient increased, litter size decreased and the percentage of stillborn puppies increased, thus indicating inbreeding depression.[85] In a study of boxer litters, 22% of puppies died before reaching 7 weeks of age.[86] Stillbirth was the most frequent cause of death, followed by infection. Mortality due to infection increased significantly with increases in inbreeding.[86]

The role of the dog in Chinese mythology includes a position as one of the twelve animals which cyclically represent years (the zodiacal dog). Three of the 88 constellations in western astronomy also represent dogs: Canis Major (the Great Dog, whose brightest star, Sirius, is also called the Dog Star), Canis Minor (the Little Dog), and Canes Venatici (the Hunting Dogs).
Unlike other domestic species which were primarily selected for production-related traits, dogs were initially selected for their behaviors.[96][97] In 2016, a study found that there were only 11 fixed genes that showed variation between wolves and dogs. These gene variations were unlikely to have been the result of natural evolution, and indicate selection on both morphology and behavior during dog domestication. These genes have been shown to affect the catecholamine synthesis pathway, with the majority of the genes affecting the fight-or-flight response[97][98] (i.e. selection for tameness), and emotional processing.[97] Dogs generally show reduced fear and aggression compared with wolves.[97][99] Some of these genes have been associated with aggression in some dog breeds, indicating their importance in both the initial domestication and then later in breed formation.[97] Traits of high sociability and lack of fear in dogs may include genetic modifications related to Williams-Beuren syndrome in humans, which cause hypersociability at the expense of problem solving ability.[100][101][102]
Citing a 2008 study, the U.S. Center for Disease Control estimated in 2015 that 4.5 million people in the USA are bitten by dogs each year.[176] A 2015 study estimated that 1.8% of the U.S. population is bitten each year.[177] In the 1980s and 1990s the US averaged 17 fatalities per year, while since 2007 this has increased to an average of 31.[178] 77% of dog bites are from the pet of family or friends, and 50% of attacks occur on the property of the dog's legal owner.[178]
The scientific evidence is mixed as to whether companionship of a dog can enhance human physical health and psychological wellbeing.[191] Studies suggesting that there are benefits to physical health and psychological wellbeing[192] have been criticised for being poorly controlled,[193] and finding that "the health of elderly people is related to their health habits and social supports but not to their ownership of, or attachment to, a companion animal." Earlier studies have shown that people who keep pet dogs or cats exhibit better mental and physical health than those who do not, making fewer visits to the doctor and being less likely to be on medication than non-guardians.[194]
^ Lindblad-Toh, K.; Wade, C.M.; Mikkelsen, T.S.; Karlsson, E.K.; Jaffe, D.B.; Kamal, M.; Clamp, M.; Chang, J.L.; Kulbokas, E.J.; Zody, M.C.; Mauceli, E.; Xie, X.; Breen, M.; Wayne, R.K.; Ostrander, E.A.; Ponting, C.P.; Galibert, F.; Smith, D.R.; Dejong, P.J.; Kirkness, E.; Alvarez, P.; Biagi, T.; Brockman, W.; Butler, J.; Chin, C.W.; Cook, A.; Cuff, J.; Daly, M.J.; Decaprio, D.; et al. (2005). "Genome sequence, comparative analysis and haplotype structure of the domestic dog". Nature. 438 (7069): 803–819. Bibcode:2005Natur.438..803L. doi:10.1038/nature04338. PMID 16341006.
The role of the dog in Chinese mythology includes a position as one of the twelve animals which cyclically represent years (the zodiacal dog). Three of the 88 constellations in western astronomy also represent dogs: Canis Major (the Great Dog, whose brightest star, Sirius, is also called the Dog Star), Canis Minor (the Little Dog), and Canes Venatici (the Hunting Dogs).

Clip the dog's nails.[3] If left untrimmed, a dog's nails can curl under into the paw pads or twist toes in a way that causes joint damage. To keep your dog's nails short, clip them regularly, depending on how fast his nails grow. If you can hear his nails on the ground when he walks, that means his nails are touching the ground, and are too long. [4]

It is a reflexive action for many dogs to try to pull away their back leg if it is lifted. Avoid lifting the leg to the side because this is uncomfortable for most dogs. Instead, pick up the foot and gently pull forward or backward. Don't be upset or punish the dog, just struggle through it and praise your dog when he or she is still. If you have a medium or large dog, you may be able to get away with clipping the nails on the hind feet without having to lift the foot.

Wolves, and their dog descendants, likely derived significant benefits from living in human camps – more safety, more reliable food, lesser caloric needs, and more chance to breed.[135] They would have benefited from humans' upright gait that gives them larger range over which to see potential predators and prey, as well as better color vision that, at least by day, gives humans better visual discrimination.[135] Camp dogs would also have benefited from human tool use, as in bringing down larger prey and controlling fire for a range of purposes.[135]
Full-service grooming cost is based on breed, pet size and type of fur or hair. It will be confirmed for you when you meet your stylist at the start of your service, and a standardized rate card based on location is available at your salon. Your stylist will consult with you before each appointment to create a personalized plan that you and your pet will be happy with!