In domestic dogs, sexual maturity happens around six to twelve months of age for both males and females,[17][68] although this can be delayed until up to two years old for some large breeds. This is the time at which female dogs will have their first estrous cycle. They will experience subsequent estrous cycles semiannually, during which the body prepares for pregnancy. At the peak of the cycle, females will come into estrus, being mentally and physically receptive to copulation.[17] Because the ova survive and are capable of being fertilized for a week after ovulation, it is possible for more than one male to sire the same litter.[17]
Take extra care with dark-nailed dogs not to clip to the quick (blood vessel). Go slowly, and only take a little bit off at a time. Dremeling is much safer and easier to avoid hitting the quick, as it shaves only a little bit at a time. Use a cordless pet-safe Dremel tool, as the corded ones will not stop turning if they catch hair. Don't dremel for too long as it will burn the nail and prolong the trimming process for the dog which causes more stress. The best recommended process is trim first then dremel to shorten a little bit and round out the nail do it's not sharp.
^ Fan, Zhenxin; Silva, Pedro; Gronau, Ilan; Wang, Shuoguo; Armero, Aitor Serres; Schweizer, Rena M.; Ramirez, Oscar; Pollinger, John; Galaverni, Marco; Ortega Del-Vecchyo, Diego; Du, Lianming; Zhang, Wenping; Zhang, Zhihe; Xing, Jinchuan; Vilà, Carles; Marques-Bonet, Tomas; Godinho, Raquel; Yue, Bisong; Wayne, Robert K. (2016). "Worldwide patterns of genomic variation and admixture in gray wolves". Genome Research. 26 (2): 163–173. doi:10.1101/gr.197517.115. PMC 4728369. PMID 26680994.

Neutering reduces problems caused by hypersexuality, especially in male dogs.[76] Spayed female dogs are less likely to develop some forms of cancer, affecting mammary glands, ovaries, and other reproductive organs.[77] However, neutering increases the risk of urinary incontinence in female dogs,[78] and prostate cancer in males,[79] as well as osteosarcoma, hemangiosarcoma, cruciate ligament rupture, obesity, and diabetes mellitus in either sex.[80]
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Toxocara canis (dog roundworm) eggs in dog feces can cause toxocariasis. In the United States, about 10,000 cases of Toxocara infection are reported in humans each year, and almost 14% of the U.S. population is infected.[185] In Great Britain, 24% of soil samples taken from public parks contained T. canis eggs.[186][failed verification] Untreated toxocariasis can cause retinal damage and decreased vision.[186] Dog feces can also contain hookworms that cause cutaneous larva migrans in humans.[187][188][189][190]

Dogs generally have brown eyes and wolves almost always have amber or light colored eyes.[49] The skin of domestic dogs tends to be thicker than that of wolves, with some Inuit tribes favoring the former for use as clothing due to its greater resistance to wear and tear in harsh weather.[50] The paws of a dog are half the size of those of a wolf, and their tails tend to curl upwards, another trait not found in wolves.[51] The dog has developed into hundreds of varied breeds, and shows more behavioral and morphological variation than any other land mammal.[52]
The role of the dog in Chinese mythology includes a position as one of the twelve animals which cyclically represent years (the zodiacal dog). Three of the 88 constellations in western astronomy also represent dogs: Canis Major (the Great Dog, whose brightest star, Sirius, is also called the Dog Star), Canis Minor (the Little Dog), and Canes Venatici (the Hunting Dogs).
Dog communication is how dogs convey information to other dogs, how they understand messages from humans, and how humans translate the information that dogs are transmitting.[103]:xii Communication behaviors of dogs include eye gaze, facial expression, vocalization, body posture (including movements of bodies and limbs) and gustatory communication (scents, pheromones and taste). Humans communicate to dogs by using vocalization, hand signals and body posture.

Wolves, and their dog descendants, likely derived significant benefits from living in human camps – more safety, more reliable food, lesser caloric needs, and more chance to breed.[135] They would have benefited from humans' upright gait that gives them larger range over which to see potential predators and prey, as well as better color vision that, at least by day, gives humans better visual discrimination.[135] Camp dogs would also have benefited from human tool use, as in bringing down larger prey and controlling fire for a range of purposes.[135]
^ Lindblad-Toh, K.; Wade, C.M.; Mikkelsen, T.S.; Karlsson, E.K.; Jaffe, D.B.; Kamal, M.; Clamp, M.; Chang, J.L.; Kulbokas, E.J.; Zody, M.C.; Mauceli, E.; Xie, X.; Breen, M.; Wayne, R.K.; Ostrander, E.A.; Ponting, C.P.; Galibert, F.; Smith, D.R.; Dejong, P.J.; Kirkness, E.; Alvarez, P.; Biagi, T.; Brockman, W.; Butler, J.; Chin, C.W.; Cook, A.; Cuff, J.; Daly, M.J.; Decaprio, D.; et al. (2005). "Genome sequence, comparative analysis and haplotype structure of the domestic dog". Nature. 438 (7069): 803–819. Bibcode:2005Natur.438..803L. doi:10.1038/nature04338. PMID 16341006.
Dogs have been described as carnivores[117][118] or omnivores.[17][119][120][121] Compared to wolves, dogs have genes involved in starch digestion that contribute to an increased ability to thrive on a starch-rich diet.[19] Based on metabolism and nutrition, many consider the dog to be an omnivore. However, the dog is not simply an omnivore. More like the cat and less like other omnivores, the dog can only produce bile acid with taurine, and it cannot produce vitamin D, which it obtains from animal flesh. Also more like the cat, the dog requires arginine to maintain its nitrogen balance. These nutritional requirements place the dog part-way between carnivores and omnivores.[122]
Cultural depictions of dogs in art extend back thousands of years to when dogs were portrayed on the walls of caves. Representations of dogs became more elaborate as individual breeds evolved and the relationships between human and canine developed. Hunting scenes were popular in the Middle Ages and the Renaissance. Dogs were depicted to symbolize guidance, protection, loyalty, fidelity, faithfulness, watchfulness, and love.[219]
Book your grooming appointment online and select the Zen Spa Package – or ask your groomer when you arrive in-store. Zen Spa package includes soothing lavender shampoo and conditioner that can help relax your pup during bath time, in addition to lavender scented spritz that refreshes coats with a fresh-smelling aromas and essential oils. Package also includes your choice of 4 basic upgrades like nail buffing, teeth brushing and paw balm, and a special seasonal bandana.