Despite their close genetic relationship and the ability to inter-breed, there are a number of diagnostic features to distinguish the gray wolves from domestic dogs. Domesticated dogs are clearly distinguishable from wolves by starch gel electrophoresis of red blood cell acid phosphatase.[41] The tympanic bullae are large, convex and almost spherical in gray wolves, while the bullae of dogs are smaller, compressed and slightly crumpled.[42] Compared with equally sized wolves, dogs tend to have 20% smaller skulls and 30% smaller brains.[43]:35 The teeth of gray wolves are also proportionately larger than those of dogs.[44] Dogs have a more domed forehead and a distinctive "stop" between forehead and nose.[45] The temporalis muscle that closes the jaws is more robust in wolves.[5]:p158 Wolves do not have dewclaws on their back legs, unless there has been admixture with dogs that had them.[46] Most dogs lack a functioning pre-caudal gland and enter estrus twice yearly, unlike gray wolves which only do so once a year.[47] So-called primitive dogs such as dingoes and Basenjis retain the yearly estrus cycle.[48]
// Forces popover to close when the user clicks anywhere on the page $(function(){ // fnGetNearestLocations(storeId, expirationMin, isHTML5Geolocation, isGoogleGeoAPI, HTML5GeoTimeout, XHRTimeout, isDebuggingEnabled) petcoNearestLocations.fnGetNearestLocations('10151','20160','true','true','10000','5000','https://www.googleapis.com/geolocation/v1/geolocate?key=','AIzaSyB1POydsXY7SJBDX-zowEC0y340ZJK6uig','false'); });
Wolves, and their dog descendants, likely derived significant benefits from living in human camps – more safety, more reliable food, lesser caloric needs, and more chance to breed.[135] They would have benefited from humans' upright gait that gives them larger range over which to see potential predators and prey, as well as better color vision that, at least by day, gives humans better visual discrimination.[135] Camp dogs would also have benefited from human tool use, as in bringing down larger prey and controlling fire for a range of purposes.[135]
Dogs have lived and worked with humans in many roles. In addition to dogs' role as companion animals, dogs have been bred for herding livestock (collies, sheepdogs),[154][17] hunting (hounds, pointers),[43] and rodent control (terriers).[17] Other types of working dogs include search and rescue dogs,[155] detection dogs trained to detect illicit drugs[156] or chemical weapons;[157] guard dogs; dogs who assist fishermen with the use of nets; and dogs that pull loads.[17] In 1957, the dog Laika became the first animal to be launched into Earth orbit, aboard the Soviets' Sputnik 2; she died during the flight.[158][159]

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Toxocara canis (dog roundworm) eggs in dog feces can cause toxocariasis. In the United States, about 10,000 cases of Toxocara infection are reported in humans each year, and almost 14% of the U.S. population is infected.[185] In Great Britain, 24% of soil samples taken from public parks contained T. canis eggs.[186][failed verification] Untreated toxocariasis can cause retinal damage and decreased vision.[186] Dog feces can also contain hookworms that cause cutaneous larva migrans in humans.[187][188][189][190]
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The cost to trim a dog’s nails can vary based on whether the dog is at a doggy day care and has the service as an add-on, whether you bring your dog to a groomer’s business, or whether you have a mobile groomer provide nail trimming at your home. Nail trimming costs less than nail grinding, which usually is done with a Dremel or similar tool. Nail trimming should be a regular part of of your dog’s care, as overgrown nails can be painful and cause problems.
Wolves kill dogs wherever they are found together.[111] One study reported that in Wisconsin in 1999 more compensation had been paid for losses due to wolves taking dogs than for wolves taking livestock. In Wisconsin wolves will often kill hunting dogs, possibly because the dogs are in the wolf's territory.[111] A strategy has been reported in Russia where one wolf lures a dog into heavy brush where another wolf waits in ambush.[112] In some instances, wolves have displayed an uncharacteristic fearlessness of humans and buildings when attacking dogs, to the extent that they have to be beaten off or killed.[113] Although the numbers of dogs killed each year are relatively low, it induces a fear of wolves entering villages and farmyards to take dogs, and losses of dogs to wolves has led to demands for more liberal wolf hunting regulations.[108]
^ Wood, Lisa; Martin, Karen; Christian, Hayley; Nathan, Andrea; Lauritsen, Claire; Houghton, Steve; Kawachi, Ichiro; McCune, Sandra (2015). "The Pet Factor – Companion Animals as a Conduit for Getting to Know People, Friendship Formation and Social Support". PLoS ONE. 10 (4): e0122085. Bibcode:2015PLoSO..1022085W. doi:10.1371/journal.pone.0122085. PMC 4414420. PMID 25924013.
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