^ Bridgett M. von Holdt, Emily Shuldiner, Ilana Janowitz Koch, Rebecca Y. Kartzinel, Andrew Hogan, Lauren Brubaker, Shelby Wanser4, Daniel Stahler, Clive D.L. Wynne, Elaine A. Ostrander, Janet S. Sinsheimer and Monique A.R. Udell (19 July 2017). "Structural variants in genes associated with human Williams-Beuren syndrome underlie stereotypical hypersociability in domestic dogs". Science Advances. 3 (7): e1700398. Bibcode:2017SciA....3E0398V. doi:10.1126/sciadv.1700398. PMC 5517105. PMID 28776031.

We are an All breed cat and dog holistic doggie daycare, Grooming boutique. We offer a unique HOLISTIC experience. We are similar to a hair salon where each pet gets extra personal attention throughout their grooming experience and doesn't have to stay for an extended time away from home.​ We use ALL natural products and offer express baths for while you wait option or Japanese Style grooming (maybe time consuming) for the frou frou dog who wants to look and feel Glamorous. ... View Profile

In domestic dogs, sexual maturity happens around six to twelve months of age for both males and females,[17][68] although this can be delayed until up to two years old for some large breeds. This is the time at which female dogs will have their first estrous cycle. They will experience subsequent estrous cycles semiannually, during which the body prepares for pregnancy. At the peak of the cycle, females will come into estrus, being mentally and physically receptive to copulation.[17] Because the ova survive and are capable of being fertilized for a week after ovulation, it is possible for more than one male to sire the same litter.[17]
^ Fan, Zhenxin; Silva, Pedro; Gronau, Ilan; Wang, Shuoguo; Armero, Aitor Serres; Schweizer, Rena M.; Ramirez, Oscar; Pollinger, John; Galaverni, Marco; Ortega Del-Vecchyo, Diego; Du, Lianming; Zhang, Wenping; Zhang, Zhihe; Xing, Jinchuan; Vilà, Carles; Marques-Bonet, Tomas; Godinho, Raquel; Yue, Bisong; Wayne, Robert K. (2016). "Worldwide patterns of genomic variation and admixture in gray wolves". Genome Research. 26 (2): 163–173. doi:10.1101/gr.197517.115. PMC 4728369. PMID 26680994.
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The scientific evidence is mixed as to whether companionship of a dog can enhance human physical health and psychological wellbeing.[191] Studies suggesting that there are benefits to physical health and psychological wellbeing[192] have been criticised for being poorly controlled,[193] and finding that "the health of elderly people is related to their health habits and social supports but not to their ownership of, or attachment to, a companion animal." Earlier studies have shown that people who keep pet dogs or cats exhibit better mental and physical health than those who do not, making fewer visits to the doctor and being less likely to be on medication than non-guardians.[194]

In mythology, dogs often serve as pets or as watchdogs.[208] Stories of dogs guarding the gates of the underworld recur throughout Indo-European mythologies[210][211] and may originate from Proto-Indo-European religion.[210][211] In Greek mythology, Cerberus is a three-headed watchdog who guards the gates of Hades.[208] In Norse mythology, a bloody, four-eyed dog called Garmr guards Helheim.[208] In Persian mythology, two four-eyed dogs guard the Chinvat Bridge.[208] In Welsh mythology, Annwn is guarded by Cŵn Annwn.[208] In Hindu mythology, Yama, the god of death, owns two watch dogs who have four eyes. They are said to watch over the gates of Naraka.[212]
The breed with the shortest lifespan (among breeds for which there is a questionnaire survey with a reasonable sample size) is the Dogue de Bordeaux, with a median longevity of about 5.2 years, but several breeds, including miniature bull terriers, bloodhounds, and Irish wolfhounds are nearly as short-lived, with median longevities of 6 to 7 years.[64]

As humans became more sophisticated, so did their dogs. Eventually, there emerged specific breeds of dogs, custom-bred to suit the breeders’ local needs and circumstances. The Greyhound, for instance, was the foundation type for the immense Irish Wolfhound and the dainty Italian Greyhound. All three have a distinct family resemblance, but you’d never mistake one for another.
^ Fan, Zhenxin; Silva, Pedro; Gronau, Ilan; Wang, Shuoguo; Armero, Aitor Serres; Schweizer, Rena M.; Ramirez, Oscar; Pollinger, John; Galaverni, Marco; Ortega Del-Vecchyo, Diego; Du, Lianming; Zhang, Wenping; Zhang, Zhihe; Xing, Jinchuan; Vilà, Carles; Marques-Bonet, Tomas; Godinho, Raquel; Yue, Bisong; Wayne, Robert K. (2016). "Worldwide patterns of genomic variation and admixture in gray wolves". Genome Research. 26 (2): 163–173. doi:10.1101/gr.197517.115. PMC 4728369. PMID 26680994.
If you are shy about touching certain parts of your dog, get over it. If you are going to clean your dog, you must clean your dog's whole body. If there are any fleas or ticks on your dog, let them sit for ten minutes after working in the flea and tick treatment shampoo. When the bugs are dead, make sure to fully wash all of them off. If they are left on, these could give your dog a disease. To get the ticks off, get your hemostats latched on the ticks head and pull outward so the head doesn't break off and stay in the body. This would include scrubbing all over your dog's body, even areas you are not comfortable with. Never use hot water, and be especially careful to avoid warm water or medicated shampoos on the genital area. This area is sensitive.

In 1999, a study of mitochondrial DNA indicated that the domestic dog may have originated from multiple grey wolf populations, with the dingo and New Guinea singing dog "breeds" having developed at a time when human populations were more isolated from each other.[23] In the third edition of Mammal Species of the World published in 2005, the mammalogist W. Christopher Wozencraft listed under the wolf Canis lupus its wild subspecies, and proposed two additional subspecies: "familiaris Linneaus, 1758 [domestic dog]" and "dingo Meyer, 1793 [domestic dog]". Wozencraft included hallstromi – the New Guinea singing dog – as a taxonomic synonym for the dingo. Wozencraft referred to the mDNA study as one of the guides in forming his decision.[1] The inclusion of familiaris and dingo under a "domestic dog" clade has been noted by other mammalogists.[24] This classification by Wozencraft is debated among zoologists.[25]
In a study of seven breeds of dogs (Bernese mountain dog, basset hound, Cairn terrier, Epagneul Breton, German Shepherd dog, Leonberger, and West Highland white terrier) it was found that inbreeding decreases litter size and survival.[84] Another analysis of data on 42,855 dachshund litters found that as the inbreeding coefficient increased, litter size decreased and the percentage of stillborn puppies increased, thus indicating inbreeding depression.[85] In a study of boxer litters, 22% of puppies died before reaching 7 weeks of age.[86] Stillbirth was the most frequent cause of death, followed by infection. Mortality due to infection increased significantly with increases in inbreeding.[86]
In the United States, cats and dogs are a factor in more than 86,000 falls each year.[183] It has been estimated around 2% of dog-related injuries treated in UK hospitals are domestic accidents. The same study found that while dog involvement in road traffic accidents was difficult to quantify, dog-associated road accidents involving injury more commonly involved two-wheeled vehicles.[184]
The most popular Korean dog dish is gaejang-guk (also called bosintang), a spicy stew meant to balance the body's heat during the summer months. Followers of the custom claim this is done to ensure good health by balancing one's gi, or vital energy of the body. A 19th century version of gaejang-guk explains that the dish is prepared by boiling dog meat with scallions and chili powder. Variations of the dish contain chicken and bamboo shoots. While the dishes are still popular in Korea with a segment of the population, dog is not as widely consumed as beef, chicken, and pork.[174]
The origin of the domestic dog includes the dog's evolutionary divergence from the wolf, its domestication, and its development into dog types and dog breeds. The dog is a member of the genus Canis, which forms part of the wolf-like canids, and was the first species and the only large carnivore to have been domesticated.[14][26] The dog and the extant gray wolf are sister taxa, as modern wolves are not closely related to the population of wolves that was first domesticated.[14]
Clean your dog's ears. It's normal for a clean ear to have some wax in it, but there shouldn't be any particular smell to it. To clean your dog's ears, apply some ear cleaning solution (bought at a pet supply store) to a cotton round. Not too much or it will drip into the ear while wiping. Wipe dirt and wax away from the inner ear, but don't rub vigorously, as this might cause sores. Don't push too far into the ear, either. If your dog has drop ears like a bassett hound, wipe the inside of the ear flag as dirt collects there as well. The groomers rule of thumb is to clean only what you can see.
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