Coyotes and big cats have also been known to attack dogs. Leopards in particular are known to have a predilection for dogs, and have been recorded to kill and consume them regardless of their size. Tigers in Manchuria, Indochina, Indonesia, and Malaysia are also reported to kill dogs. Striped hyenas are known to kill dogs in Turkmenistan, India, and the Caucasus.
Clip the dog's nails. If left untrimmed, a dog's nails can curl under into the paw pads or twist toes in a way that causes joint damage. To keep your dog's nails short, clip them regularly, depending on how fast his nails grow. If you can hear his nails on the ground when he walks, that means his nails are touching the ground, and are too long. 
Comb out your dog first. Combing your dog's coat daily or every other day will keep most mats at bay. Simply brushing, as most literature instructs, is not enough for dogs that can mat up: the brush will easily pass over at angles that a comb will get stuck on. A thorough combing should always be the first step of the grooming process because any mats will become tighter and less manageable once they dry. Begin on the head and move down the body. Be careful under the belly, as it is a sensitive area, and don't forget to comb the tail.
Dogs bear their litters roughly 58 to 68 days after fertilization, with an average of 63 days, although the length of gestation can vary. An average litter consists of about six puppies, though this number may vary widely based on the breed of dog. In general, toy dogs produce from one to four puppies in each litter, while much larger breeds may average as many as twelve.
Wolves, and their dog descendants, likely derived significant benefits from living in human camps – more safety, more reliable food, lesser caloric needs, and more chance to breed. They would have benefited from humans' upright gait that gives them larger range over which to see potential predators and prey, as well as better color vision that, at least by day, gives humans better visual discrimination. Camp dogs would also have benefited from human tool use, as in bringing down larger prey and controlling fire for a range of purposes.
The price of dog grooming starts around $40 for a full grooming service for a small dog, and around $75 for a large dog. If you have more than one, prices can be significantly lower for the second and third dog. For mobile grooming, where groomers come to you, a full service of ears, nails, anal glands, bath, blow dry, and scissor finish is about $75 for average size dogs.
^ Bridgett M. von Holdt, Emily Shuldiner, Ilana Janowitz Koch, Rebecca Y. Kartzinel, Andrew Hogan, Lauren Brubaker, Shelby Wanser4, Daniel Stahler, Clive D.L. Wynne, Elaine A. Ostrander, Janet S. Sinsheimer and Monique A.R. Udell (19 July 2017). "Structural variants in genes associated with human Williams-Beuren syndrome underlie stereotypical hypersociability in domestic dogs". Science Advances. 3 (7): e1700398. Bibcode:2017SciA....3E0398V. doi:10.1126/sciadv.1700398. PMC 5517105. PMID 28776031.
Neutering reduces problems caused by hypersexuality, especially in male dogs. Spayed female dogs are less likely to develop some forms of cancer, affecting mammary glands, ovaries, and other reproductive organs. However, neutering increases the risk of urinary incontinence in female dogs, and prostate cancer in males, as well as osteosarcoma, hemangiosarcoma, cruciate ligament rupture, obesity, and diabetes mellitus in either sex.