Dogs bear their litters roughly 58 to 68 days after fertilization,[17][71] with an average of 63 days, although the length of gestation can vary. An average litter consists of about six puppies,[72] though this number may vary widely based on the breed of dog. In general, toy dogs produce from one to four puppies in each litter, while much larger breeds may average as many as twelve.
^ Lindblad-Toh, K.; Wade, C.M.; Mikkelsen, T.S.; Karlsson, E.K.; Jaffe, D.B.; Kamal, M.; Clamp, M.; Chang, J.L.; Kulbokas, E.J.; Zody, M.C.; Mauceli, E.; Xie, X.; Breen, M.; Wayne, R.K.; Ostrander, E.A.; Ponting, C.P.; Galibert, F.; Smith, D.R.; Dejong, P.J.; Kirkness, E.; Alvarez, P.; Biagi, T.; Brockman, W.; Butler, J.; Chin, C.W.; Cook, A.; Cuff, J.; Daly, M.J.; Decaprio, D.; et al. (2005). "Genome sequence, comparative analysis and haplotype structure of the domestic dog". Nature. 438 (7069): 803–819. Bibcode:2005Natur.438..803L. doi:10.1038/nature04338. PMID 16341006.

The genetic divergence between dogs and wolves occurred between 40,000–20,000 years ago, just before or during the Last Glacial Maximum.[27][2] This timespan represents the upper time-limit for the commencement of domestication because it is the time of divergence and not the time of domestication, which occurred later.[27][28] The domestication of animals commenced over 15,000 years ago, beginning with the grey wolf (Canis lupus) by nomadic hunter-gatherers.[27] The archaeological record and genetic analysis show the remains of the Bonn–Oberkassel dog buried beside humans 14,200 years ago to be the first undisputed dog, with disputed remains occurring 36,000 years ago.[2] It was not until 11,000 years ago that people living in the Near East entered into relationships with wild populations of aurochs, boar, sheep, and goats.[27]

It has been suggested that the most significant benefit would have been the use of dogs' robust sense of smell to assist with the hunt.[136] The relationship between the presence of a dog and success in the hunt is often mentioned as a primary reason for the domestication of the wolf, and a 2004 study of hunter groups with and without a dog gives quantitative support to the hypothesis that the benefits of cooperative hunting was an important factor in wolf domestication.[137]
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You may need to pluck ear hairs from time to time. Ask a veterinarian or professional groomer to show you how to pluck the hairs from your dog's ear safely and correctly. Ear powder makes the process easier and quicker by giving added gripping power to the slippery ear hairs. Be very careful when using hemostats as they may poke inside their ear if used incorrectly or when the dog jerks their head.

The most popular Korean dog dish is gaejang-guk (also called bosintang), a spicy stew meant to balance the body's heat during the summer months. Followers of the custom claim this is done to ensure good health by balancing one's gi, or vital energy of the body. A 19th century version of gaejang-guk explains that the dish is prepared by boiling dog meat with scallions and chili powder. Variations of the dish contain chicken and bamboo shoots. While the dishes are still popular in Korea with a segment of the population, dog is not as widely consumed as beef, chicken, and pork.[174]
The longest-lived breeds, including toy poodles, Japanese spitz, Border terriers, and Tibetan spaniels, have median longevities of 14 to 15 years.[64] The median longevity of mixed-breed dogs, taken as an average of all sizes, is one or more years longer than that of purebred dogs when all breeds are averaged.[62][63][64][65] The longest-lived dog was "Bluey", an Australian Cattle Dog who died in 1939 at 29.5 years of age.[66][67]
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The health benefits of dogs can result from contact with dogs in general, and not solely from having dogs as pets. For example, when in the presence of a pet dog, people show reductions in cardiovascular, behavioral, and psychological indicators of anxiety.[197] Other health benefits are gained from exposure to immune-stimulating microorganisms, which, according to the hygiene hypothesis, can protect against allergies and autoimmune diseases. The benefits of contact with a dog also include social support, as dogs are able to not only provide companionship and social support themselves, but also to act as facilitators of social interactions between humans.[198] One study indicated that wheelchair users experience more positive social interactions with strangers when they are accompanied by a dog than when they are not.[199] In 2015, a study found that pet owners were significantly more likely to get to know people in their neighborhood than non-pet owners.[200]
Brush the dog's teeth.[2] Ideally, brushing your dog’s teeth every day with dog toothpaste is the route to healthy teeth and gums. Use dog toothpaste instead of human products, so you don't poison your dog with fluoride. If there is any chance that you may get bitten by your dog, do NOT attempt to brush your pet’s teeth. At any point, if the dog gets overwhelmed, give him a break to calm down.

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